As the recreational and medicinal use of marijuana increases around the world, the concern for families has expanded. Around the world, countries and states have recently legalized or are on the path to legalizing or decriminalizing the consumption of marijuana (cannabis). This trend has led to more lactation support providers and healthcare professionals being faced with the question, “Is it safe to use marijuana during human milk feeding?” The answers given vary widely and this is due largely to myth, bias, and poorly conducted and accessed research. The Medications and Mother’s Milk Guide considers cannabis to be an L4 while Lactnet states that it is preferable for users to continue breastfeeding and yet minimize the baby’s exposure to smoke. Differing recommendations lead healthcare professionals to scratch their heads and face the knowledge that they just don’t know what to say to mothers. Additionally, there are reports of social services removing babies from homes due to parental marijuana use while breastfeeding. An entirely newly discovered system (the endocannabinoid system) within the human interacts with marijuana and is largely responsible for brain development, homeostasis, and much more. Discover how and why cannabis chemicals can potentially change a babies brain development and epigenome. This presentation looks at the most recent research, policies, and equity issues surrounding this controversial herb.