As the use of cannabis increases, the concern for families has expanded. Many countries and states have recently legalized or decriminalized the consumption of cannabis. This trend has led to more healthcare professionals being faced with the question, “Is it safe to use cannabis during lactation?” The answers given vary widely and this is due largely to myth, bias, and poorly conducted research. Differing recommendations lead healthcare professionals to scratch their heads and face the knowledge that they just don’t know what to say to families. Additionally, there are reports of social services removing babies from homes due to parental cannabis use while breast/chestfeeding. The human endocannabinoid system interacts with cannabis and is largely responsible for brain development, homeostasis, and much more. Unfortunately, a risk reduction instead of evidence-based harm reduction has been the standard of care. Discover what is known about cannabis chemicals and baby’s short and long-term health when cannabis is used during lactation. This presentation looks at the most recent research, policies, harm reduction practices, and equity issues surrounding this controversial herb.