New mothers are often advised to avoid nighttime breastfeeding in order to prevent postpartum depression. While this advice is well-intended, no one knows if it even works. And it can be quite problematic for breastfeeding mothers to maintain. Using data from the Survey of Mothers’ Sleep and Fatigue, we examine the relationship between feeding method, depression, and maternal fatigue. Consistent with recent studies, our findings reveal that breastfeeding mothers report less fatigue, more and better quality sleep, and lower rates of depression than their formula- or mixed-feeding counterparts. Advising tired new mothers to supplement may well increase their risk of depression. This presentation also summarizes some strategies that can be used to support exhausted new mothers.