Dysphoric Milk Ejection Reflex (D-MER) is an abrupt emotional “drop” that occurs in some women just before milk release and continues for not more than a few minutes. The brief negative feelings range in severity from wistfulness to self-loathing, and appear to have a physiological cause. The authors suggest that an abrupt drop in dopamine may occur when milk release is triggered, resulting in a real or relative brief dopamine deficit for affected women. Clinicians can support women with D-MER in several ways; often, simply knowing that it is a recognized phenomenon makes the condition tolerable. Further study is needed.

Dysphoric Milk Ejection Reflex (D-MER) is a condition affecting lactating women that is characterized by an abrupt dysphoria, or negative emotions, that occur just before milk release and continuing not more than a few minutes. Before The Letdown is eleven chapters of information for mothers looking for support and understanding, for care providers who want to know how to best support their patients and for partners and family members who want to know how to best support a mother with D-MER. The book is written by Alia Macrina Heise, IBCLC who has been the forerunner in discovering and identifying D-MER since 2007. It includes a preface by internationally renowned lactation author and presenter, Diane Wiessinger, MS, IBCLC and is edited by Dr. Marcelina Watkinson, DClinPsy who did the first qualitative research study on D-MER.